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Created with Fabric.js 1.4.5 Harlequin Ichyosis About It the disorder is very rareworldwide. an estimated that 100 people are affected. All You Need To Know History information the disorder appears in the chromosome 18 and this disorder is so rare that there is no paticular ethic gorups that in falls in On Thursday, April the 5th, 1750,I went to see a most deplorable object of a child, born the night before of one Mary Evans in 'Chas'town. It was surprising to all who beheld it, and I scarcely know how to describe it. The skin was dry and hard and seemed to be cracked in many places, somewhat resembling the scales of a fish. The mouth was large and round and open. It had no external nose, but two holes where the nose should have been. The eyes appeared to be lumps of coagulated blood, turned out, about the bigness of a plum, ghastly to behold. It had no external ears, but holes where the ears should be. The hands and feet appeared to be swollen, were cramped up and felt quite hard. The back part of the head was much open. It made a strange kind of noise, very low, which I cannot describe. It lived about forty-eight hours The disorder is inherited in many different way s either by dominate,recessseive ,sex linked or Xlinked the symptoms are dry, textures, scaly skin.poorly deloped ears and protruded becomes very weak.and skin becomes redden with sparse the doctors deal with infections
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