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Created with Fabric.js 1.4.5 Escitalopram LEXAPRO MECHANISM OF ACTION ' DOSAGE SPECIAL POPULATIONS Escitalopram is in a class of drugs called selective serotonin reuptake inhibitors (SSRIs). Chemical messengers travel to nearby nerves and attach to their receptors however, not all of the neurotransmitters that are released will bind to the receptors, and may instead be naturally absorbed back into the nerve cells of the brain (referred to as reuptake). SSRIs work to block this reabsorption. Temporarily keeping the neurotransmitters in the synapse helps brain cells send and receive Prescription antidepressant used to treat major depressive disorder and generalized anxiety disorder ADMINISTRATION Oral tablets: contain escitalopram oxalate (equivalent to a 5 mg, 10 mg and 15 mg escitalopram base) Oral solution: liquid solution containing escitalopram oxalate (equivalent to 1 mg/ml escitalopram base). Adolescents: 10 mg once daily Adults: 10 mg once daily PHARMACOKINETICS Absorption: Lexapro is absorbed in 3-4 hours after single or multiple-dose administration Distribution: Distributed widely throughout tissues, with an apparent volume of distribution during the terminal phase afteroral administration (V(z)/F) of about 1100L. Metabolism: Lexapro is metabolized to S-DCT and S-didemethylcitalopram (S-DDCT). Excretion: Lexapro is eliminated from the body principally in urine in about 27-33 hours with once-daily administration. Hepatic impairment: 10 mg once dailyGeriatric patients: 10 mg once daily CLINICAL STUDIES Major Depressive Disorder and Generalized Anxiety Disorder Adolescents and Adults: Lexapro showed statistically significant greater meanimprovement compared to the placebo. double click to change this title text! INDICATIONS/USAGE chemical messages, which in turn, boosts the mood. WARNINGS Worsening of depression and risk of suicideSerotonin Syndrome Neuroleptic Malignant Syndrome-like ReactionsAbnormal bleedingInterference with cognitive and motor functions 10 tablets/10 mgEscitalopram: $15.00-$20.00Lexapro: $50.00-$75.00 CONTRAINDICATIONS Used for the acute treatment and maintenance of major depressive disorder and generalized anxiety disorder in adults and in adolescents 12-17 years old -Monoamine oxidase inhibitors (MAOIs)-Pimozide-Hypersensitivity to escitalopram or citalopram Sarah Pearose
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