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Created with Fabric.js 1.4.5 DRUG RELATED PROBLEMS IN ONCOHAEMATOLOGIC OUTPATIENTS INCLUDED IN CLINICAL TRIALS BACKGROUND To quantify and to analyze drug related problems (DRPs) in oncohaematologic outpatients included in clinical trials and to measure their knowledge about the treatment. DescriptiveCross-sectional study Lack of knowledge about their treatment is oneof the main elements leading to an inappropriate use of medicines by patients. When starting a clinical trial, outpatients receive a large amount of information, which is sometimes difficult tounderstand. PURPOSE MATERIALS AND METHODS MARCH 2014 APRIL Oncohaematologicoutpatients initiatingtreatment with oral investigational products (IP) or been taking the treatment less thanthree months ago from the time of inclusion VARIABLES - Age - Sex- Diagnosis- Department- Previous participations in clinical trials- Prescribed medication- DRPs- Knowledge about their treatment - Pharmaceutical interventions RESULTS 26 patients 73.1% 26.9% Mean age 59.8 - 84.6% belonged to the Oncology department -The main diagnosis: breast cancer: 11 (42.3%) patients - 15 (57.7%) patients started treatment with IP- 5 (19.2%) had previously participated in another clinical trial B Montero Pastor, M Muñoz GarcíaME Carretero Accame, M Sánchez Cuervo C Pueyo López, I Cuesta López T Bermejo Vicedo 32 INVESTIGATIONAL PRODUCTS (29.3%) - 10 DRP were detected in 7 (26.9%) patients- Of all, 6 (60%) were due to the IP A total of 109 drugswere evaluated Adverse events40% Interactions40% Misprescription10% Incorrect self-administration10% DRPs detected CONCLUSIONS The high prevalence of DRPs detected emphasizes the necessity to implement specific Pharmaceutical Care programs to adequately inform patients included in clinical trials, preventing and detecting DRPs, especially when starting new treatments PS-037
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