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Created with Fabric.js 1.4.5 double click to changethis text! Drag a cornerto scale proportionally. Tizanidine Hepatic Impairment Renal Impairment Elderly Pharmacokinetics 2mg capsule is $451.91 for 150 capsules4mg capsule is $572.81 for 150 capsules 2mg tablet is $183.28 for 150 tablets 4mg tablet is $219.76 for 150 tablets Trade Name: Zanaflex Contradictions CYP1A2 Inhibitors Hallucinations Special Populations Warnings/ Indications/ Drowsiness Muscle Spasticity Usage: - Placebo and Tizanidine pills were randomized -118 Patients 7-Week Clinical Study - 4 Weeks:Measured muscle tone on maximally - 3 Weeks:10mg in the morning and afternoon Precautions: Hypotension Pregnacy (Category C) Liver Injury Bioavailability is 40%. Can be administered with or with out food.30% bound to plasma proteins.Mostly metabolized in the liver.20% found in feces and 60% in urine. Tizanidine is a central alpha-2-adrenergic receptor agonist and attempts to reduce spasticity by increasing the presynaptic inhibition of the motor neurons in the brain. The initial dosage if 4mg PO q6-8hr PRN for muscle spasms. The dosage should not exceed more than 3 doses or more than 36mg in a 24 hour period. This medication is not recommended to pediatric dosing. CNS Depressants Oral Contraceptives tolerated dose. and 16mg in the evening Cost: Audrey SkoggGonzalez, Pd.5 Hypersensitivity Absorption: Distribution: Metabolism: Excretion: A2-Adrenergic Agonists
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