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Created with Fabric.js 1.4.5 Small Pox A serious, contagious disease that was often lethal tap and hold to change this header text! Dating all the way back to 1350 B.C.E, during the Egyptian-Hittite War What is the cause? Variola minor Caused by the variola virus, there are two variations The most dangerous version,where 30% infected died Less than 1% of infected dead How does it spread? The virus spreads through contact and saliva droplets in an infected persons mouth Variola tend to enter though the respiratory tract. They attach to the mouth,lung mucosa or trachea. The cells made up of mucous membrane are not compact, which is why they are able to penetrate saliva. Once the virus reaches the cell membrane, it is taken in through endocytisis. When in the host cell, the core protein is released Signs and Symptoms high fever.chills.headache.severe back pain.abdominal pain.vomiting. Who's infected? An estimated 300-500 million died from smallpox in the 20th century How is it diagnosed? Isolation of virus from blood or lesions Identifying antibodies in the blood made due to the virus Diagnosing smallpox occurs in labs to protect workers Variola virus is isolated in labs usingthe highest biosafety levels (Biosafety level IV) How is it treated? The first successful vaccination was discovered by Edward Jenner in 1796, it involved cowpox pus into a open wound, the patient would then become resistant or immune to smallpox The vaccine is very effective if used withinfour days of infection There is no cure for small pox but the vaccine is capable of eradicating the disease Can it be prevented? tap and hold to change this header text! If the vaccine is used within four days ofInfection There are no public health policies or campaigns to raise awareness as the disease has been eradicated since 1980
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