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Created with Fabric.js 1.4.5 SYSTEMIC LUPUS ERYTHEMATOSUS WORLD TRADE CENTER HEALTH REGISTRY WHAT IS LUPUS? WHAT COULD CAUSE LUPUS? GENES ENVIRONMENT HORMONES MEDICATIONS WHO IS AFECTED? Estimated 1.5 MILLION Americans have Lupus of people with lupus are women. Men can also develop Lupus. If your parents or a sibling has Lupus, your chances jump to 1 in 25 Black and Latina women 1 in 250 chance of have a developing the disease. If you're a woman with no family history of Lupus your chances are 1 in with no family history of Lupus 400 Sulfa drugs, tetracyclines, and certain antibiotics can cause Lupus. WHO IS AFFECTED? Estimated 1.5 MILLION 90% Men Emotional stress, exposure to ultraviolet rays, pregnancy, and giving birth are risk factors. Onset ages 15 to 44 Lupus is a chronic, autoimmune disease that can damage any part of the body. Chronic means that the signs and symptoms tend to last longer than six weeks and often for many years. In Lupus, something goes wrong with your immune system, which is the part of the body that fights off viruses, bacteria, and germs. Normally our immune system produces proteins called antibodies that protect the body from these invaders. Autoimmune means your immune system cannot tell the difference between these foreign invaders and your bodys healthy tissues, so it attacks and destroys healthy tissue. This causes inflammation, pain, and damage in various parts of the body. YOU SHOULD KNOW Lupus is NOT contagious, not even through sexual contact. You cannot "catch" or "give" lupus to someone. Lupus is NOT like or related to Cancer, HIV(Human Immune Deficiency Virus) or AIDS (Acquired Immune Deficiency Syndrome). There is currently no cure for Lupus,but its symptoms can be controlled with good management and therapy. There are three other types of Lupus; Cutaneous,Lupus which only affects the skin; Drug-Induced Lupus, which is caused by allergies to certain medications; and Neonatal Lupus, which is rare andoccurs in infants born to mothers who have Lupus. No two Lupus cases are alike. Every case hasa different combination of symptoms, and symptomscan mimic or overlap other immune diseases, like Rheumatoid Arthritis and Sjogren's Syndrome. 4 Sunlight sensitivity, or scaly rash on, neck, ears, scalp, or chest. Butterfly-shaped rash on face. Headaches and difficulty with memory or concentration, or numbness of limbs. Kidney disease that leads to weight gain and swelling. Stabbing chest painor shortness ofbreath. Arthritis (pain and swelling in joints). Sudden pain in left sideof chest, or bloodproblems like anemiaor low white cellcount. SYMPTOMS OR MORE OF THESE SYMPTOMS ARE PRESENT, YOU SHOULD SEE A RHEUMATOLOGIST IF DIAGNOSIS TREATMENT different strategies varydepending on the particular symptoms of every patient.Medications include: is only confirmed with x-raysand blood tests, like: - Antinuclear antibody test- Specific antibodies like anti-dsDNA, anti-phospholipid,and anti-smith.- Skin or kidney sample. - Nonsteroidal Anti-inflammatory drugs.- Antimalarial drugs- Immune suppressants- Corticosteroids References/Web Links - http://www.lupus.org- http://www. niams.nih.gov- http://www.clevelandclinic.org/healthhub- http://emedicine.medscape.com/article/332244-overview
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