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Created with Fabric.js 1.4.5 HEMOLYTIC UREMIC SYNDROME Condition that results from the abnormal premature destruction of RBCs.These RBCs clog the filtering system of the kidneys and it may be life threatening.It is also associated with hemolytic anemia, thrombocytopenia, and neurologic or renal abnormalities Typical: 0.5-2.1 cases per 100,000 pop. per year with a peak incidence in children youngerthan 5 yrs.Atypical: 5-10% of all cases; 2 cases per 100,000 per year The most common cause in children is an infection with a type of E. Coli known as 0157:H7 that was from raw meat or a dirty pool for example; other strains of E.Coli have been linked as well. In adults, it has been caused by taking certain meds. (ike chemotherapy, quinine, and anti-platelet); pregnancy; infections (HIV etc.); genes; however it is often idiopathic. Fluid Replacement: Kidneys aren't being regulated properly;RBC Transfusions;Platelet Transfusions;Plasma Exchange;Kidney Dialysis: (To filter wastes) or a possible kidney transplantEculizumab (Soliris) for tx of atypical HUS but it may lead to sever susceptibility to infection;People who have long lasting kidney damage should follow a low-protein diet and take ACE inhibitors to prevent further kidney damage. S/S: Bloody diarrhea, vomiting, abdominal pain, pale skin, fatigue, irritability, fever, bld in urine, small unexplained bruises, decreased urination or bld in urine, edema, confusion.Bld Tests:Decreased platelet count, decreased RBC count, or higher creatinine.Urine Tests: To test the bldStool Sample:To test for bacteria Try to prevent food-borne illnesses from E. Coli by washing you hands, utensils and surfaces often; keep raw foods away from other foods; Defrost raw meat in microwave or fridge; thoroughly cook ground beef; wash fruits and veggies; avoid unpasteurized milk, juice, and cidar; avoid swimming in water contaminated with feces; wash hands before eating; and wash hands when you get out of the restroom. Most people fully recover if they have the proper tx, but it depends on the severity of their condition. A kidney transplant may cause all these issues to disappear; there is a better prognosis for children DESCRIPTION: TRANSMISSION/CAUSES: OCCURENCE: MANIFESTATION/Dx: TREATMENTS: CURES: PREVENTION: By: Tatiana Blanco
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