Infographic Template Galleries

Created with Fabric.js 1.4.5 TRADE NAME: AUGMENTINGENERIC NAME:AMOXICILLIN AND CLAVULANATE POTASSIUM TRADE NAME: AUGMENTINGENERIC NAME:AMOXICILLIN AND CLAVULANATE POTASSIUM Oral ROUTE OF ADMINISTRATION COMMON DOSAGE MECHANISM OF ACTION PHARMACOKINETICS SPECIAL POPULATIONS CLINICAL STUDIES INDICATIONS/USAGE CONTRAINDICATIONS WARNINGS/PRECAUTIONS For film-coated tablets- one 500-mg tablet of AUGMENTIN q12hor one 250-mg tablet q8h - People with allergies to penicillins,history of cholestatic jaundice/hepatic dysfunction -penicillin-binding proteinsare bound to amoxicillin-clavulanate hinders beta-lactamase-producing bacteria: allows amoxicillin an extended spectrum of action-semisynthetic antibiotic Sept.,1999: trial using 84-volunteers to test the usefulness of generic drug for children with acute otitis media.-primary outcome: amount of time for middle ear effusion to disappear-secondary outcome: amount of time for pain to disappear -pregnant women(drug past through breast milk; lactation)-hepatic impairment, hemodialysis patients-peds pts <16 yrs old (unknown for extended-release tabs) 500mg-125mg for 20 tabs is $1,029.08,875mg-125mg for 20 tabs is 1,372.17 COST Treats many bacteria causedinfections. For example, pneumonia, ear infections, bronchitis, UTIs, and skin infections -Risk of CDAD-allergies to cephalosporins-different tabs not interchangeable due to different ratios-risk of superinfections(fungal or bacterial)-increased risk of hypatic dysfunction with prolonged therapy Carla Leal-WillettMs.Gonzalez, p.1 -ABSORPTIONPeak Plasma Time:amoxicillin(2 hr)clavulanic acid(1.1hr)-DISTRIBUTIONbesides CNS, widelydistributed-METABOLISMLiver partially metabolizes-EXCRETION unchanged urine: amoxicillin(50-70%), clavulanate acid(25-40%)
Create Your Free Infographic!