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Created with Fabric.js 1.4.5 Function:regulates T-cell activation, and is anaccessory protein for T-cell receptor interaction Found in: Helper T-cells, some cytotoxic T-cells Megan Wadleigh,Walid Rafei,Aliyah Cooglerperiod 3 wake up CD4 Reference Info:CD4 - T-cell surface glycoprotein CD4 precursor - Homo sapiens (Human). (n.d.). Retrieved March 3, 2015, from CD4 Count, HIV, and AIDS: Test and Results -- What They Mean. (n.d.). Retrieved March 3, 2015, from INTERESTING FACTST cell (T lymphocyte) Any of a population of lymphocytes that are the principal agents of cell-mediated immunity. T cells are derived from the bone marrow but migrate to the thymus to mature (hence T cell). Subpopulations of T cells play different roles in the immune response and can be characterized by their surface antigens (see CD). Helper T cells recognize foreign antigens provided these are presented by cells (such as macrophages and B lymphocytes) bearing class II histocompatibility (MHC) proteins (see histocompatibility). The helper T cell carries T-cell receptors, which recognize the class II MHC proteins on the antigen-presenting cell. Interleukin-1 released by inducer cells stimulates helper T cells to release interleukin-2, which in turn triggers the release of other cytokines (see interleukin). Consequently there is a proliferation of B lymphocytes and the generation of effector T cells, i.e. cytotoxic T cells, delayed hypersensitivity T cells, and suppressor T cells.
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